Evaluation of RDT-based algorithms to diagnose chronic T. cruzi infection in endemic countries as an alternative to the current (laboratory-based) diagnostic pattern

FIND. Venue: BRAZIL, BOLIVIA, AND COLOMBIA

Area of Activity: Diagnóstico y/o biomarcadores
Type of Project: Research & Translation
CD rapid diagnostic tests (RDTs) are available in endemic countries, but their use for screening is limited. Evidence suggests that RDTs could be used to diagnose CD.
 
RDT-based algorithms could allow implemention of a point-of-care diagnostic test, increasing adoption of a test-and-treat strategy for chronic CD in endemic regions.
 
We will conduct two consecutive multicenter prospective field studies to evaluate the use of RDT-based algorithms to diagnose chronic CD in endemic countries as an alternative to the current (laboratory-based) diagnostic patterns in Bolivia, Brazil and Colombia.
 
Partner institutions:

Consortium composed by: Oswaldo Cruz Foundation – MoH (Fiocruz), Brazil (leading team) - Instituto Nacional de Salud (INS), Colombia - Instituto Nacional de Laboratorios de Salud (INLASA), Bolivia - FIND, Geneva, Switzerland.